Figure 4. Predictive value of βIII-tubulin expression for response to docetaxel in castration-resistant prostate cancer patients.

A, B. Representative staining for βIII-tubulin in prostate biopsy cores: absence of staining (A), staining positivity (B). Photomicrographs are taken at x20 objective magnification (A–B), insets x5 objective magnification (AC). Scale Bar, 100μm.
C. Overall survival in docetaxel-treated patients: stratification by βIII-tubulin expression in prostatic tissue (negativity versus positivity of immunostaining, log-rank test; p=0.019): expression of βIII-tubulin in prostate cancer tissue is significantly predictive for poorer survival in docetaxel-treated patients.