Table 2. Changes in personality scores in the escitalopram and the placebo group following four weeks of treatment.
| Personality trait(4 weeks -entry) | Interventiongroup | Mean (SD) | Median | Minimumvalue | Maximumvalue | Interquartile range | p |
| Neuroticismc | Escitalopram | −1.77 (3.74) | −1 | −9 | 12 | 4 | |
| Placebo | −2.08 (2.86) | −2 | −9 | 4 | 4 | 0.73b | |
| Neuroticismd | Escitalopram | −3.01 (10.3) | −4 | −31 | 19 | 10 | |
| Placebo | 1.00 (10.5) | 1 | −21 | 27 | 16 | 0.09a | |
| Extraversiond | Escitalopram | 1.51 (7.95) | 2 | −16 | 18 | 10 | 0.90a |
| Placebo | 1.32 (6.24) | 2 | −15 | 15 | 8 | ||
| Opennessd | Escitalopram | 3.18 (9.84) | 5 | −30 | 20 | 8 | 0.33b |
| Placebo | 2.15 (9.97) | 3 | −17 | 38 | 14 | ||
| Agreeablenessd | Escitalopram | 2.38 (8.09) | 1 | −18 | 19 | 11 | 0.046a |
| Placebo | −1.32 (7.94) | −3 | −15 | 18 | 11 | ||
| Conscientiousnessd | Escitalopram | 1.85 (8.41) | 2 | −12 | 20 | 14 | 0.07a |
| Placebo | −2.34 (11.4) | −1 | −42 | 14 | 14 |
a
) The distributions did not differ significantly from the normal distribution (Shapiro Wilkes test) and a t-test was used to compare the escitalopram and the placebo arm. P of Levene's test ranged from 0.11 to 0.80.
b
) The distributions differed from the normal distribution but judged from the graphical displays (histograms and probability distributions) they followed normal distributions with reasonable approximation, thus a t-test was also used.
c
) Eysenck: Escitalopram (n = 39), placebo (n = 37).
d
) NEO-PI-R: Escitalopram (n = 39), placebo (n = 38).