Table 1. Genes most highly induced or inhibited in HUVEC cultures 8 h after NiV infection.
FC | Common name | GenBank N° | Description | Function |
23.3 | PTPRM | AI669006 | protein tyrosine phosphatase, receptor type, M | cellular growth and proliferation |
23.2 | MxA; IFI78; IFI-78K | AF135187 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 | immune response |
19.8 | IFIT1; G10P1; IFI56; IFNAI1; GARG-16 | NM_001548 | interferon-induced protein with tetratricopeptide repeats 1 | immune response |
14.5 | IFI44L; GS3686; C1orf29 | NM_006820 | interferon-induced protein 44-like | immune response |
14.2 | BRESI1 | NM_033255 | epithelial stromal interaction 1 (breast) | connective tissue disorder |
11.6 | MGC116903; MGC116904 | NM_000811 | gamma-aminobutyric acid (GABA) A receptor, alpha 6 | neurological disease |
11.4 | cig5; vig1; 2510004L01Rik | NM_080657 | radical S-adenosyl methionine domain containing 2 | viral function |
10.9 | CXCL10; IFI10; IP-10 | NM_001565 | chemokine (C-X-C motif) ligand 10 | immune response |
10.9 | OASL; TRIP14 | NM_003733 | 2′-5′-oligoadenylate synthetase-like | immune response |
10.8 | RIG-G; IRG2; IFI60; ISG60; GARG-49 | NM_001549 | interferon-induced protein with tetratricopeptide repeats 3 | immune response |
10.4 | IFIT2; G10P2; IFI54; GARG-39; ISG-54K | NM_001547 | interferon-induced protein with tetratricopeptide repeats 2 | immune response |
10.3 | OAS2; MGC78578 | NM_002535 | 2′-5′-oligoadenylate synthetase 2, 69/71 kDa | immune response |
8.6 | OAS1 | AU076579 | 2′,5′-oligoadenylate synthetase 1, 40/46 kDa | immune response |
5.8 | BAL; BAL1; | NM_031458 | poly (ADP-ribose) polymerase family, member 9 | cellular movement |
5.7 | IFI44; p44; MTAP44 | NM_006417 | interferon-induced protein 44 | immune response |
−5.4 | LGALS3 | AF031424 | Homo sapiens galectin 3 (LGALS3) gene, exon 5. | immune response |
−7.6 | TAF4B | AA457205 | TAF4b RNA polymerase II, TATA box binding protein ass factor, 105 kDa | cell signaling |
−8 | ATP13A4 | AW073336 | ATPase type 13A4 | unknown |
−10.3 | BX108708 | Transcribed locus | unknown | |
−12.3 | IDS | AK126415 | CDNA FLJ44451 fis, UTERU2023039 | unknown |
−13 | BF476432 | CDNA FLJ38408 fis, FEBRA2009029 | unknown | |
−14.8 | AI255115 | Transcribed locus | unknown | |
−17.9 | CTS9 | NM_017418 | deleted in esophageal cancer 1 | cancer |
−25.1 | FLJ22318; DKFZp434K0926 | NM_022762 | hypothetical protein FLJ22318 | unknown |
−32.1 | MGC3035 | NM_024293 | chromosome 2 open reading frame 17 | unknown |
−44 | BBS4 | BF370543 | Bardet-Biedl syndrome 4 | cancer |
−46.7 | FLJ12986 | AK126695 | hypothetical protein FLJ12986 | unknown |
FC: Fold Change; induction of the level of gene expression in NiV-infected cells in comparison to mock-infected cells as determined by microarray analysis. Only changes higher then 5.7 and lower then −5.4 are presented.