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. 2012 Feb 29;7(2):e30201. doi: 10.1371/journal.pone.0030201

Table 1. Lethal Factor is measurable in the ear, draining cervical lymph nodes and serum at the time of debridement 12 hours after spore inoculation.

Strain EarC cLNC D Serum/mlC
BIG23A 458±216 28±10 476±82
TKOB 1592±681 49±13 2354±223
A

Injection of 1×106 luminescent 7702 (BIG23) spores subcutaneously into left ear of 3 A/J mice.

B

Injection of 1×106 triple exotoxin knockout (TKO) spores with 100 ng LF plus 650 ng PA into left ear of 3 A/J mice.

C

LF detected by anatomic locations (pg/tissue ± SE) 12 hours post inoculation. Average of three separate experiments with three mice.

D

Cervical lymph node.