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. 1991 Nov 11;19(21):6041–6046. doi: 10.1093/nar/19.21.6041

1H NMR of 5'CGCGTATATACGCG3', a duplex and a four-membered loop.

D A Kallick 1, D E Wemmer 1
PMCID: PMC329064  PMID: 1945888

Abstract

The deoxyribonucleotide 5'CGCGTATATACGCG3' was synthesized and studied by NMR methods. This short, fully palindromic duplex also forms a hairpin under certain conditions described within. As such, it is considered to be a model for cruciform formation. We show that this sequence forms a four-membered loop and a duplex in solution. The duplex is shown to be a normal, B-DNA like helix, while the hairpin is shown to be a four-membered ATAT loop.

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Selected References

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