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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Cytokine. 2012 Jan 15;58(1):20–26. doi: 10.1016/j.cyto.2011.12.017

Figure 3.

Figure 3

IL-4δ2 and IL-4 protein levels, as determined by ELISA, in purified primary T cell culture supernates from asthma patients and healthy controls following stimulation with PMA/ionomycin at indicated times (h). Cytokine levels (pg/ml) in individual cultures are shown. Levels of IL-4δ2 (A) and IL-4 (B) proteins in T cell culture supernates from the same 5 patients with asthma (solid lines) and from 2 healthy controls (dashed lines) as in Figure 2 are shown. In panel C, the levels of IL-4δ2 and IL-4 were also measured in additional primary T cell cultures at 48 h and 72 h for a total of 11 patients with asthma (1 mild, 8 moderate, and 2 severe) and 5 healthy controls. The significance of differences in the cytokine production levels at the measured times was assessed using the Wilcoxon signed rank test.