Table 1.
Means and standard deviations (SD) for variables describing total sample (n=62) at baseline and over individualized follow-up.
| Mean | SD | |
|---|---|---|
| Age (years) (baseline) | 78.7 | 5.5 |
| Education (years) | 15.0 | 3.0 |
| Mattis DRS total (baseline) | 136.1 | 5.0 |
|
| ||
| Longitudinal Measures | ||
| High LEDS ratings | 3.3 | 3.1 |
| Diurnal cortisol (nmol/L) | 5.7 | 1.8 |
| CAR (% change) | 21.1 | 51.5 |
| Post-peak cortisol (nmol/L) | 3.3 | 1.3 |
| Follow-up interval (years) | 2.5 | 1.1 |
|
| ||
| Percentage of Subjects | ||
| MCI versus CN (baseline) | 53.2 | |
| Female | 56.5 | |
| ≥ 1 APOE-e4 | 45.2 | |
DRS = Mattis Dementia Rating Scale
LEDS = Life Events and Difficulties Schedule
Diurnal cortisol=mean of samples (awakening, 30 minutes later, 2 PM, 4 PM, bedtime)
CAR = Cortisol Awakening Response; percent change from awakening to 30 minutes later
Post-peak cortisol = mean of the 2 PM, 4 PM, and bedtime measures
APOE-e4 = Apolipoprotein-E e4 allele