ASO468
|
TGACCCAAGATGGCGGCCGG |
ASO targeting PCA3 at the region immediately 3’ to nt 468 |
ASO683
|
TGCCATCAAGATTTTCTCGTC |
ASO targeting PCA3 at the region immediately 3’ to nt 683 |
ASO735
|
GCT GCC TCA TGT CAT CAC AG |
ASO targeting PCA3 at the region immediately 3’ to nt 735 |
ASO735 MM1 |
GCT GCC TCA TCT CAT CAC AG |
Single-nt mismatch of ASO735
|
ASO735 MM2A |
GCT GCC TCA TCT CAT CAC GG |
Two-nt mismatch of ASO735
|
ASO735 MM2B |
GCT GCC TCA TCG CAT CAC AG |
Two-nt mismatch of ASO735
|
ASO735 MM4 |
GCT GCC TCA TCG AGT CAC AG |
Four-nt mismatch of ASO735
|
DNA mimic of PCA3 |
CTG TGA TGA CAT GAG GCA GCT TTT TGA CGA GAA AAT CTT GAT GGC |
45-nt sequence containing the two portions of PCA3 that the ASOs were complementary to, separated by 5 T's |
ASOT683
|
(TTT) TTT TTT TTG CCA TCA AGA TTT TCT CGTC |
ASO683 with 7 or 10 Ts added at the 5’ end as noted |
ASOT735
|
(TTT) TTT TTT TGC TGC CTC ATG TCA TCA CAG |
ASO735 with 7 or 10 Ts added at the 5’ end as noted |
ASOnon
|
CTC GTA TCT CAA CTC GTA TTT TTT TTT TTT |
Non-complementary probe sequence |