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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Hippocampus. 2011 Nov 11;22(6):1481–1491. doi: 10.1002/hipo.20987

Figure 3.

Figure 3

Experiment 1 – Freezing behavior and locomotor activity. Freezing behavior: Effects of pre-training postsubiculum (PoSub) lesions on freezing behavior of lesioned (n = 14) and Sham-operated (n = 20) groups during the Acquisition session (A) and during the Context (B) and Tone (C) tests. BL, baseline; PS1 – 3, postshock 1 – 3. Bilateral lesions of the PoSub significantly decreased postshock freezing during training as well as freezing behavior during the Context and Tone tests (ps < 0.001). Locomotor activity: Average open field activity depicting that PoSub lesioned-rats (n = 11) were hyperactive compared to Sham-operated rats (n = 12) and that both groups habituated to the open-field over time (D). Relationship between freezing behavior and locomotor activity. Postshock freezing data from PoSub-lesioned rats was divided into normo-active (PoSub-Low, n = 5) and hyperactive (PoSub-High, n = 6) groups and replotted for the Acquisition session (E) and the Context (F) and Tone (G) tests. Replotted locomotor activity of normo-active and hyperactive groups (H). Data represent means ± standard errors. **p <05 compared to Sham-operated and PoSub-Low groups. # indicates that PoSub-lesioned rats showed a trend toward less freezing compared with Sham-operated rats (ps=0.06).