Figure.

A_[MH2], 3D mesh images of the head viewed from the top, arrow indicating the forehead. Illustration of the average mesh image for severity scores 0=‘none’, 1=‘mild’, 2=‘moderate’, 3=‘severe’ from expert clinician ratings.B, Surface normal vectors of points that lie on a rounded surface have a wider distribution of angles as illustrated for the head on the extreme left, andthose that lie on a flat surface tend to have similar azimuth and elevation angles as illustrated for the head on the extreme right. C, Posterior flattening and average (standard deviation) z-scores for the PF, AAS, CI and aOCLR for the 3D mesh images above, now viewed from the back. Posterior flattening is depicted using a color map where high score values are represented by warm colors (red, orange, yellow), and low score values correspond to cool colors (blue, cyan, green). A representative unaffected control participant is shown at the extreme left. All index scores for this infant are near 0, shown by the cool coloring at the posterior. A case infant is shown at the extreme right, with elevated index scores and flattening severity depicted by red coloring on the affected side.