. Author manuscript; available in PMC: 2012 Sep 1.

Published in final edited form as: Nat Cell Biol. 2012 Feb 12;14(3):311–317. doi: 10.1038/ncb2440

Table 1. Plk1 dissociates dynactin-dynein from LGN-NuMA complex.

Summary of mass spectrometry data showing the percent sequence coverage for the proteins that co-purify with GFP-LGN, but not controls, in the presence or absence of treatment with Plk1 and ATP.

Protein	GFP-LGN IP (% Seq. Coverage)		Molecular Weight (kD)
Protein	−Plk1	+Plk1	Molecular Weight (kD)
LGN	63.9	63.0	76.6
NuMA	56.7	56.9	238.3
Dynactin1, p150	7.4		141.6
Dynactin2, p50	42.1		44.8
Dynactin3	19.3		19.4
Dynactin, Arp1A	25.3		42.6
Dynein 1 heavy. Chain 1	4.8		532.4
Dynein 1 Light Inter. Chain 1	16.6		56.6
Dynein 1 Light Inter. Chain 2	3.7		54.0