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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: J Neuroimaging. 2011 Aug 19;22(3):e12–e19. doi: 10.1111/j.1552-6569.2011.00629.x

Table 2.

Comparison of reliability of normalization techniques

% COV
intra-rater		 ICC intra-
rater		 % COV
inter-rater		 ICC inter-
rater
C2-3 spinal cord volume normalized to # of slices 1.24 0.939 4.22 0.184
C2-3 volume normalized to # of slices and ICV 1.36 0.987 4.03 0.902
Whole cord raw volume 0.52 0.996 0.66 0.987
Whole cord volume normalized to # of slices 0.61 0.988 0.74 0.982
Whole cord volume normalized to ICV 0.44 0.997 1.30 0.990
Whole cord volume normalized to ICV and number of slices 0.53 0.998 1.34 0.994
ICV 0.11 0.9998 1.42 0.999

COV=coefficient of variation, ICC=intraclass correlation coefficient for consistency, ICV=intracranial volume