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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: J Neuroimaging. 2011 Aug 19;22(3):e12–e19. doi: 10.1111/j.1552-6569.2011.00629.x

Table 5.

Correlations between MRI-based spinal cord volumes and neurologic disability

Region Volume Correlation (rs)
with EDSS
p-
value
Correlation (rs)
with T25FW
p-
value
C2-3 Normalized to # of slices −0.509 0.002 −0.424 0.012
Normalized to # of slices and ICV −0.451 0.007 −0.400 0.019
Cervical cord Raw −0.401 0.019 −0.272 0.120
Normalized to ICV −0.428 0.012 −0.297 0.088
Normalized to # of slices −0.450 0.008 −0.352 0.041
Normalized to # of slices and ICV −0.420 0.013 −0.334 0.054
Thoracic cord Raw −0.296 0.089 −0.269 0.124
Normalized to ICV −0.298 0.087 −0.295 0.091
Normalized to # of slices −0.258 0.141 −0.229 0.193
Normalized to # of slices and ICV −0.286 0.102 −0.209 0.237
Whole cord Raw −0.330 0.057 −0.268 0.125
Normalized to ICV −0.373 0.030 −0.303 0.081
Normalized to # of slices −0.339 0.050 −0.230 0.191
Normalized to # of slices and ICV −0.354 0.040 −0.256 0.144

ICV=intracranial volume, EDSS=Expanded Disability Status Scale, T25FW=Timed 25 Foot Walk, rs=Spearman’s correlation coefficient.