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. Author manuscript; available in PMC: 2013 Feb 9.
Published in final edited form as: Oncogene. 2011 Nov 28;31(32):3721–3732. doi: 10.1038/onc.2011.534

Figure 5. MDMX level has significant impact on ARF-mediated growth arrest.

Figure 5

(a) U2OS cells stably transfected with MDMX cDNA (U2OS-MDMX) or MDMX shRNA (U2OS-shRNA) expression plasmids were infected with adenovirus-ARF at indicated MOI and analyzed by western blot after 24 hrs. (b) Cells with MDMX overexpression or knockdown were infected with adenovirus ARF for 24 hrs. Cells were labeled with BrdU for 2 hrs (n=4) and analyzed for DNA replication rate using a BrdU detection ELISA kit.