Table 3.
PC, sample | SNP | Chr | position | Code d allele | Non-Code d allele | Coded allele frequenc y | LD | pval | beta | h2q | In/near gene* |
---|---|---|---|---|---|---|---|---|---|---|---|
PC2, women | rs9351097 | 6 | 87194834 | T | G | 0.175 | -- | 3.40 * 10− | 0.252 | 0.0164 | HTR1E |
PC2, women | rs9362321 | 6 | 87192966 | T | C | 0.174 | 0.838 | 4.30 * 10−8 | 0.246 | 0.0162 | HTR1E |
PC2, women | rs9362322 | 6 | 87197144 | A | T | 0.196 | 0.838 | 9.30*10−8 | 0.242 | 0.0154 | HTR1E |
PC2, women | rs9362320 | 6 | 87192883 | T | C | 0.018 | 0.096 | 6.00*10−7 | 0.648 | 0.0135 | HTR1E |
PC2, women | rs6919366 | 6 | 87169891 | G | T | 0.337 | 0.336 | 9.30*10−7 | 0.176 | 0.0130 | HTR1E |
PC4, combined | rs6911565 | 6 | 87557585 | A | C | 0.137 | 0.178 | 1.10*10−5 | −0.19 | 0.0081 | HTR1E |
PC4, combined | rs12665525 | 6 | 87553199 | C | T | 0.117 | 0.178 | 3.20*10−5 | −0.18 | 0.0073 | HTR1E |
PC2, combined | rs7158720 | 14 | 32347622 | A | C | 0.209 | -- | 1.40*10−7 | 0.161 | 0.0086 | AKAP6 |
PC2, women | rs7158720 | 14 | 32347622 | A | C | 0.208 | -- | 4.10*10−5 | 0.167 | 0.0091 | AKAP6 |
PC2, combined | rs10148694 | 14 | 32343262 | T | C | 0.358 | 0.464 | 2.40*10−5 | 0.112 | 0.0055 | AKAP6 |
PC4, women | rs4773155 | 13 | 109780420 | A | C | 0.432 | -- | 2.50 * 10−8 | 0.356 | 0.0204 | COL4A2 |
PC4, women | rs4447275 | 13 | 109769067 | G | A | 0.462 | 0.533 | 5.30*10−7 | −0.272 | 0.0166 | COL4A2 |
LD: linkage disequilibrium with the most-significant SNP
h2q - variance explained by a SNP
distance from the nearest gene was assumed not to exceed 500kb.