Table 3.

Comparison of the performance of the predictive models after adding the biomarkers

Model	Biomarker (p value)	AIC	H-L test (p value)	AUC (95% CI)	NRI (p value)	IDI (p value)
Clinical model	–	197.2	0.01	0.79 (0.70–0.89)	–	–
Clinical + uNGAL	0.0008	188.7	0.21	0.82 (0.73–0.91)	0.38 (0.04)	0.06 (0.04)
Clinical + pNGAL	0.052	195.5	0.01	0.81 (0.72–0.90)*	0.42 (0.02)	0.02 (0.28)
Clinical + uCyC	0.76	199.1	0.01	0.79 (0.70–0.89)	−0.25 (0.17)	0.0004 (0.88)
Clinical + pCyC	0.006	191.3	0.02	0.81 (0.72–0.90)	0.08 (0.67)	0.04 (0.09)

H-L = Hosmer-Lemeshow.

^*p < 0.05 for improvement in AUC vs. clinical model alone.