Fig. 2.
Population frequencies of wild-type CYP2C9 (*1/*1) and VKORC1 (c.−1639G/G) individuals (gray) and those carrying variant CYP2C9 (*2, *3, *4, *5, *6, *8, and *11) and/or VKORC1 (c.−1639G>A) alleles (black). Note the significantly higher frequency of African-Americans who are wild-type for both CYP2C9 and VKORC1 (59%) compared with other studied populations (13–22%; P < 0.0001). Adapted from Scott et al., 2010.58