Table 2.

Hazard Ratios and 95% Confidence Intervals for the Association of Thyroid Cancer With Self-reported Medical Conditions, US Radiologic Technologists Study, 1983–2006

	Women			Men
	No. of Casesa	HR	95% CI	No. of Casesa	HR	95% CI
Goiterb
Never diagnosed	218	1.00	Reference	35	1.00	Reference
Ever diagnosed	20	4.10	2.58, 6.49	1	9.28	1.25, 69.17
Hyperthyroidismb
Never diagnosed	226	1.00	Reference	36
Ever diagnosed	11	2.05	1.12, 3.76	0
Hypothyroidismb
Never diagnosed	213	1.00	Reference	35	1.00	Reference
Ever diagnosed	24	1.31	0.85, 2.02	1	1.72	0.23, 12.69
Thyroiditisb,c
Never diagnosed	214	1.00	Reference	35
Ever diagnosed	3	1.69	0.54, 5.30	0
Thyroid nodule/adenomab,d
Never diagnosed	95	1.00	Reference	13	1.00	Reference
Ever diagnosed	21	6.88	4.28, 11.06	3	32.75	9.12, 117.53
Any benign thyroid conditionb,e
Never diagnosed	182	1.00	Reference	32	1.00	Reference
Ever diagnosed	56	2.35	1.73, 3.20	4	4.65	1.62, 13.34
Thyroid hormone use in the past yearb,d
No use + never diagnosed with a benign thyroid conditione	80	1.00	Reference	12	1.00	Reference
No use + ever diagnosed with a benign thyroid conditione	15	3.93	2.26, 6.85	0
Used	21	2.89	1.77, 4.71	3	16.18	4.45, 58.89
Arthritis, rheumatoidd,f
Never diagnosed	113	1.00	Reference	26
Ever diagnosed	3	0.92	0.29, 2.90	0
Arthritis, otherd,f
Never diagnosed	94	1.00	Reference	14	1.00	Reference
Ever diagnosed	22	1.31	0.80, 2.15	2	1.10	0.24, 5.01
Asthmad,f
Never diagnosed	99	1.00	Reference	14	1.00	Reference
Ever diagnosed	17	1.68	1.00, 2.83	2	1.49	0.33, 6.62
Benign breast disease (i.e., fibrocystic)d,f
Never diagnosed	63	1.00	Reference
Ever diagnosed	53	1.56	1.08, 2.26
Cholesterol, elevated (≥240 mg/dL)d,f
Never diagnosed	110	1.00	Reference	13	1.00	Reference
Ever diagnosed	6	0.47	0.20, 1.09	3	1.63	0.45, 5.90
Chronic bronchitisd,f
Never diagnosed	108	1.00	Reference	16
Ever diagnosed	8	0.94	0.46, 1.95	0
Diabetes mellitusd,f
Never diagnosed	112	1.00	Reference	16
Ever diagnosed	4	1.37	0.49, 3.77	0
Hypertensiond,f
Never diagnosed	113	1.00	Reference	16
Ever diagnosed	3	1.02	0.32, 3.29	0
Ulcerd,f
Never diagnosed	105	1.00	Reference	14	1.00	Reference
Ever diagnosed	11	0.88	0.47, 1.65	2	0.99	0.22, 4.54

Abbreviations: CI, confidence interval; HR, hazard ratio.

^aNumber of cases may be inconsistent because of missing values.

^bAdjusted for birth year, smoking status, body mass index, number of personal radiographs to the head or neck, and cumulative occupational radiation dose.

^cCollected in only the first questionnaire (1983–1984) (86.8% of the study population).

^dCollected in only the second questionnaire (1994–1998) (89.6% of the study population).

^eSelf-reported history of goiter, hyperthyroidism, hypothyroidism, thyroiditis, or benign nodules or adenomas.

^fAdditionally adjusted for medical history of benign thyroid conditions.