Table 4.

Results of Sensitivity Analysis for Unmeasured Confounding of the Estradiol-Cholesterol Association by Plasma Volume Among Women Participating in the BioCycle Study, Buffalo, New York, 2005–2007

Effect of High Plasma Volume on Lipoprotein Cholesterol Level, mg/dLa	Difference in Prevalence of High Plasma Volume for High Fiber Intake (≥22 g/day) vs. Low Fiber Intake (<22 g/day)b
	Total Cholesterol			Low Density Lipoprotein Cholesterol
	Estradiol Level 30 pg/mL	Estradiol Level 45 pg/mL	Estradiol Level 110 pg/mL	Estradiol Level 30 pg/mL	Estradiol Level 45 pg/mL	Estradiol Level 110 pg/mL
1	−7.70c	−7.22	−6.26	−6.23	−6.33	−6.53
5	−1.56	−1.46	−1.27	−1.27	−1.29	−1.33
6	−1.30	−1.22	−1.06	−1.06	−1.08	−1.12
7	−1.12	−1.05	−0.91	−0.92	−0.93	−0.96
8	−0.98	−0.92	−0.80	−0.81	−0.82	−0.84
9	−0.88	−0.82	−0.71	−0.72	−0.73	−0.75
10	−0.79	−0.74	−0.64	−0.65	−0.66	−0.68
11	−0.72	−0.68	−0.59	−0.59	−0.60	−0.62
12	−0.66	−0.62	−0.54	−0.55	−0.56	−0.57
13	−0.61	−0.58	−0.50	−0.51	−0.52	−0.53
14	−0.57	−0.54	−0.46	−0.47	−0.48	−0.50
15	−0.54	−0.50	−0.44	−0.44	−0.45	−0.47
20	−0.41	−0.38	−0.33	−0.34	−0.35	−0.36

^aThe effect of high plasma volume on lipoprotein cholesterol levels is conditional on fiber intake, estradiol levels, and covariates.

^bDifferences in the prevalence of high plasma volume comparing high fiber intake with low fiber intake are conditional on the levels of estradiol and covariates.

^cThe absolute value of difference in prevalence cannot be greater than 1. Therefore, for small effects of high plasma volume on lipoprotein cholesterol, there is no prevalence difference that would eliminate the observed effects.