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Effects of zerumbone on the caspase-3 activity and the generation of ROS production of PNAC-1 cells. (a) Zerumbone increased the caspase-3 activity of PANC-1 cells. n = 3 independent experiments. (b) Zerumbone 30 μM increased the fluorescence density of ROS. Zerumbone increased the ROS generation in a concentration-dependent manner. n = 4 independent experiments, *P < 0.05 versus Control.
