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. 2012 Feb 9;2012:821967. doi: 10.1155/2012/821967

Figure 1.

Figure 1

Changes in severity scores and ear thickness of atopic dermatitis (AD) in NC/Nga mice. AD was induced in Nc/Nga mice by topical application of 2,4-dinitrochlorobenzene (DNCB) in the dorsal skin, and a right ear was topically treated with 1,3-butylen glycol (BG; control), 5% Chrysanthemum indicum L. (CIL-Low), 30% Chrysanthemum indicum L. (CIL-High), and 0.1% hydrocortisone (HC) on the lesions for 5 weeks. Normal controls did not have DCNB-induced AD. CIL decreased clinical severity of atopic dermatitis symptoms and ear thickness in a dose-dependent manner, and CIL-High had a statistically similar effect on the severity as HC. (a) Changes in severity scores. (b) Changes of ear thickness. Each value represents the mean ± SD of 10 mice in each group. *Significantly different among the different treatments in Nc/Nga mice at P < 0.05. a, b, c Values with different superscripts were significantly different among Nc/Nga mice by Tukey test at P < 0.05. †Significantly different between control (BG) and normal control at P < 0.05.