TABLE 2.
153Sm-EDTMP treatment | Patient no. | Tumor no. | Tumor mass (g) | Mean absorbed dose (Gy) | Mean biologically effective dose (Gy) | Equivalent uniform dose (Gy) | Percentage tumor volume reduction | Overall treatment response |
---|---|---|---|---|---|---|---|---|
Low administered activity | 1 | 1 | 65.2 | 1.80 | 1.81 | 1.22 | −56.4 | Progressive disease |
2 | 1 | 210 | 14.6 | 15.1 | 3.87 | −95.2 | Progressive disease | |
2 | 10.9 | 1.48 | 1.48 | 0.98 | −218 | |||
3 | 1 | 633 | 2.06 | 2.06 | 1.50 | −19.5 | Progressive disease | |
4 | 1 | 482 | 2.85 | 2.88 | 2.30 | −73.6 | Progressive disease | |
5 | 1 | 43.2 | 5.45 | 5.50 | 3.90 | −195 | Progressive disease | |
2 | 25.1 | 3.18 | 3.16 | 2.06 | −66.7 | |||
High administered activity | 1 | 1 | 132 | 4.93 | 5.06 | 3.25 | NA | Progressive disease |
2 | 1 | 379 | 59.3 | 87.3 | 12.3 | 10.7 | Stable disease | |
2 | 20.6 | 21.9 | 32.2 | 6.76 | 36.4 | |||
3 | 18.3 | 28.4 | 35.9 | 8.29 | 33.8 | |||
4 | 21.6 | 28.6 | 45.5 | 5.88 | 10.5 | |||
5 | 1 | 266 | 21.6 | 22.3 | 9.17 | −21.0 | Stable disease | |
2 | 36.3 | 23.8 | 24.7 | 8.42 | 38.2 | |||
6 | 1 | 25.1 | 2.93 | 2.96 | 1.89 | NA | Progressive disease | |
2 | 15.0 | 3.09 | 3.13 | 2.30 | NA | |||
3 | 23.6 | 3.13 | 3.15 | 2.16 | NA | |||
4 | 18.0 | 5.45 | 5.62 | 2.32 | NA | |||
5 | 41.4 | 3.33 | 3.35 | 1.95 | NA |
NA = not available.