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. 2012 Feb 12;2012:836759. doi: 10.1155/2012/836759

Figure 4.

Figure 4

Inhibition of PTP enhances Ang-1-induced Akt and eNOS phosphorylation under HG conditions. (a) Western blot showing that pretreatment of MHMEC with the PTP inhibitor orthovanadate (OV, 5 μM) for 30 minutes leads to an increase in Akt phosphorylation in response to Ang-1 (250 ng/mL) stimulation under high glucose conditions (n = 3, *P < 0.05). (b) Western blot showing that pretreatment of MHMEC with the PTP inhibitor OV for 30 minutes results in a significant increase in Ang-1-induced eNOS phosphorylation under high glucose conditions (n = 3, *P < 0.05).