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. 2012 Feb 28;7(2):e32533. doi: 10.1371/journal.pone.0032533

Table 2. Performance of CKD-Epi and aMDRD equations in predicting GFR at inclusion in 111 ADPKD patients as a whole and ranked according to mGFR<70 (n = 45) and ≥70 (n = 66) mL/min/1.73 m2.

Overall mGFR<70 mGFR≥70
CKD-Epi Estimated GFR 81.37±29.39 52.85±12.58 100.82±20.18
Bias 2.81±12.32 0.85±7.99 4.15±14.46
Mean % Error 3.84±15.74 2.15±14.91 4.98±16.30
Mean Absolute % Error 12.50±10.24 11.94±9.01 12.88±11.06
Scatter 7.01 4.69 9.88
Mean Absolute Differences 9.58±8.20 6.26±4.96 11.84±9.18
Estimates within 10% 51.35 51.11 51.52
Pearson Coefficient 0.908 0.775 0.715
Lin Coefficient 0.899 0.760 0.692
aMDRD Estimated GFR 73.01±27.95* 47.82±10.39* 90.18±22.59°
Bias −5.55±12.79 −4.17±7.08 −6.49±15.51
Mean % Error −6.93±14.69 −7.23±13.01 −6.72±15.82
Mean Absolute % Error 13.32±9.23 11.76±9.01 14.38±9.29
Scatter 8.92 4.60 11.24
Mean Absolute Differences 10.76±8.82 6.34±5.18 13.77±9.53
Estimates within 10% 41.44 51.11 34.85
Pearson Coefficient 0.891 0.770 0.729
Lin Coefficient 0.872 0.712 0.672

Iohexol plasma clearance: overall: 78.56±26.70 mL/min/1.73 m2; GFR<70: 51.99±10.49 mL/min/1.73 m2; GFR≥70: 96.67±17.63 mL/min/1.73 m2.

Data are mean±SD or median.

Estimated GFR, Bias, Scatter and Mean Absolute Differences are in mL/min/1.73 m2.

*

p<0.001;

°

p<0.01;

p<0.05 vs. iohexol plasma clearance.