Table 2. Performance of CKD-Epi and aMDRD equations in predicting GFR at inclusion in 111 ADPKD patients as a whole and ranked according to mGFR<70 (n = 45) and ≥70 (n = 66) mL/min/1.73 m2.
Overall | mGFR<70 | mGFR≥70 | ||
CKD-Epi | Estimated GFR | 81.37±29.39∧ | 52.85±12.58 | 100.82±20.18∧ |
Bias | 2.81±12.32 | 0.85±7.99 | 4.15±14.46 | |
Mean % Error | 3.84±15.74 | 2.15±14.91 | 4.98±16.30 | |
Mean Absolute % Error | 12.50±10.24 | 11.94±9.01 | 12.88±11.06 | |
Scatter | 7.01 | 4.69 | 9.88 | |
Mean Absolute Differences | 9.58±8.20 | 6.26±4.96 | 11.84±9.18 | |
Estimates within 10% | 51.35 | 51.11 | 51.52 | |
Pearson Coefficient | 0.908 | 0.775 | 0.715 | |
Lin Coefficient | 0.899 | 0.760 | 0.692 | |
aMDRD | Estimated GFR | 73.01±27.95* | 47.82±10.39* | 90.18±22.59° |
Bias | −5.55±12.79 | −4.17±7.08 | −6.49±15.51 | |
Mean % Error | −6.93±14.69 | −7.23±13.01 | −6.72±15.82 | |
Mean Absolute % Error | 13.32±9.23 | 11.76±9.01 | 14.38±9.29 | |
Scatter | 8.92 | 4.60 | 11.24 | |
Mean Absolute Differences | 10.76±8.82 | 6.34±5.18 | 13.77±9.53 | |
Estimates within 10% | 41.44 | 51.11 | 34.85 | |
Pearson Coefficient | 0.891 | 0.770 | 0.729 | |
Lin Coefficient | 0.872 | 0.712 | 0.672 |
Iohexol plasma clearance: overall: 78.56±26.70 mL/min/1.73 m2; GFR<70: 51.99±10.49 mL/min/1.73 m2; GFR≥70: 96.67±17.63 mL/min/1.73 m2.
Data are mean±SD or median.
Estimated GFR, Bias, Scatter and Mean Absolute Differences are in mL/min/1.73 m2.
p<0.001;
p<0.01;
p<0.05 vs. iohexol plasma clearance.