Table. National history and timing of symptom onset for index patients (secondary pneumonic plague) versus caregiver-patients (primary pneumonic plague), Uganda, December 2004.

Symptoms†	Patient‡	Symptom onset by day of illness*
		1		2		3		4		5		6		7		8		9
		AM	PM	AM	PM	AM	PM	AM	PM	AM	PM	AM	PM	AM	PM	AM	PM	AM		PM
Fever/chills	A1	X
	B1	X
	A2	O
	B2	O
Headache	A1	X
	B1	X
	A2	O
	B2	O
Lymphadenopathy	A1					X
	B1	Unknown
	A2	None
	B2	None
Weakness	A1							X
	B1				X
	A2	O
	B2	O
Cough	A1									X
	B1								X
	A2	O
	B2		O
Chest pain	A1									X
	B1												X§
	A2	O
	B2	O
Productive cough	A1													X
	B1									X
	A2	O
	B2		O
Bloody sputum	A1															X
	B1											X
	A2				O
	B2		O
Shortness of breath	A1
	B1											X
	A2			O
	B2			O
Nonambulatory	A1
	B1													X
	A2					O
	B2	Never
Death/effective																		X¶
treatment	B1														X¶
	A2						O¶
	B2				O#

*X, secondary pneumonic plague index patient; O, primary pneumonic plague caregiver-patient. AM, symptom first appeared between midnight and noon; PM, symptom first appeared between noon and midnight.
†Additional symptoms: caregiver A2 had a sore throat and ulcerative pharyngitis. Caregiver B2 had a burning back pain that started at the time of illness onset. Index patients A1 and B1 both had vomiting, and B1 also had diarrhea.
‡Cases are listed by time of onset: 12/9 (A1), 12/13 (B1), 12/23 (A2), 12/25 (B2). Caregiver A2 reported her husband was ill about midday on 12/23, but symptoms might have started earlier. Caregiver A2 was index patient A1's mother and her primary caregiver during her illness. Caregiver B2 was index patient B1's sister and his primary caregiver during his illness.
§Patient B1 first reported to family members severe chest pain on day 6 of illness but might have had mild chest pain earlier.
¶Death.
#Treatment and survival.