Table 1.
Effect of paeonol on the histopathological scores in lipopolysaccharide-induced acute lung injury.
| Cellularity | Protein exudation | Hemorrhage | Scores | |
|---|---|---|---|---|
| PBS-DMSO | 7.2 ± 1.0 | 3.8 ± 0.6 | 8.1 ± 1.8 | 19.0 ± 2.5 |
| PBS-paeonol | 4.5 ± 0.2 | 2.7 ± 0.6 | 7.8 ± 0.7 | 14.9 ± 1.2 |
| LPS-DMSO | 18.0 ± 0.7 | 10.9 ± 0.8 | 16.4 ± 1.0 | 45.4 ± 1.0 |
| LPS-paeonol-25 | 10.8 ± 0.9# | 4.5 ± 0.8# | 11.5 ± 1.5 | 26.8 ± 2.4# |
| LPS-paeonol-50 | 9.1 ± 1.2# | 4.1 ± 0.4# | 10.5 ± 1.5# | 23.7 ± 2.9# |
Data are presented as mean ± SEM; PBS-DMSO: PBS-DMSO group; PBS-paeonol: PBS-paeonol group; LPS-DMSO: LPS-DMSO group; LPS-paeonol-25: LPS-paeonol-25 mg/kg group; LPS-paeonol-50: LPS-paeonol-50 mg/kg group; # P < 0.05 compared with LPS-DMSO; n = 6.