Table 2. Genotype frequencies of SNPs of the IL10 gene among cases (n=288) and controls (n=310).
|
|
|
|
Genotype Frequency, n (%) |
|
Allele 1 Dominant Model, n (%) |
|
Allele 1 Recessive Model, n (%) |
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rsID | Allele 1>2 | Status | 1/1 | 1/2 | 2/2 | p | 1/1+1/2 | 2/2 | p | 1/1 | 1/2+2/2 | p | |||||||
|
rs1878672 |
C>G |
Cases |
258 |
(89.6) |
29 |
(10.1) |
1 |
(0.3) |
0.650 |
287 |
(99.7) |
1 |
(0.3) |
0.602 |
258 |
(89.6) |
30 |
(10.4) |
0.392 |
| |
|
Controls |
269 |
(87.3) |
37 |
(12.0) |
2 |
(0.7) |
|
306 |
(99.4) |
2 |
(0.7) |
|
269 |
(87.3) |
39 |
(12.7) |
|
|
rs1554286 |
T>C |
Cases |
135 |
(46.9) |
125 |
(43.4) |
28 |
(9.7) |
0.640 |
260 |
(90.3) |
28 |
(9.7) |
0.524 |
135 |
(46.9) |
153 |
(53.1) |
0.389 |
| |
|
Controls |
134 |
(43.4) |
140 |
(45.3) |
35 |
(11.3) |
|
274 |
(88.7) |
35 |
(11.3) |
|
134 |
(43.4) |
175 |
(56.6) |
|
|
rs1518111 |
A>G |
Cases |
136 |
(47.2) |
124 |
(43.1) |
28 |
(9.7) |
0.574 |
260 |
(90.3) |
28 |
(9.7) |
0.515 |
136 |
(47.2) |
152 |
(52.8) |
0.322 |
| |
|
Controls |
133 |
(43.2) |
140 |
(45.5) |
35 |
(11.4) |
|
273 |
(88.6) |
35 |
(11.4) |
|
133 |
(43.2) |
175 |
(56.8) |
|
|
rs3021094 |
A>C |
Cases |
105 |
(36.5) |
142 |
(49.3) |
41 |
(14.2) |
0.0523 |
247 |
(85.8) |
41 |
(14.2) |
0.236 |
105 |
(36.5) |
183 |
(63.5) |
0.118 |
| |
|
Controls |
132 |
(42.7) |
122 |
(39.5) |
55 |
(17.8) |
|
254 |
(82.2) |
55 |
(17.8) |
|
132 |
(42.7) |
177 |
(57.3) |
|
|
rs3790622 |
C>T |
Cases |
254 |
(88.2) |
32 |
(11.1) |
2 |
(0.7) |
0.576 |
286 |
(99.3) |
2 |
(0.7) |
0.524 |
254 |
(88.2) |
34 |
(11.8) |
0.343 |
| |
|
Controls |
279 |
(90.6) |
28 |
(9.1) |
1 |
(0.3) |
|
307 |
(99.7) |
1 |
(0.3) |
|
279 |
(90.6) |
29 |
(9.4) |
|
|
rs3024490 |
T>G |
Cases |
129 |
(44.8) |
127 |
(44.1) |
32 |
(11.1) |
0.486 |
256 |
(88.9) |
32 |
(11.1) |
0.343 |
129 |
(44.8) |
159 |
(55.2) |
0.315 |
| |
|
Controls |
125 |
(40.7) |
140 |
(45.6) |
42 |
(13.7) |
|
265 |
(86.3) |
42 |
(13.7) |
|
125 |
(40.7) |
182 |
(59.3) |
|
|
rs1800872 |
A>C |
Cases |
136 |
(47.2) |
124 |
(43.1) |
28 |
(9.7) |
0.507 |
260 |
(90.3) |
28 |
(9.7) |
0.438 |
136 |
(47.2) |
152 |
(52.8) |
0.284 |
| |
|
Controls |
132 |
(42.9) |
140 |
(45.5) |
36 |
(11.7) |
|
272 |
(88.3) |
36 |
(11.7) |
|
132 |
(42.9) |
176 |
(57.1) |
|
|
rs1800871 |
T>C |
Cases |
136 |
(47.4) |
123 |
(42.9) |
28 |
(9.8) |
0.557 |
259 |
(90.2) |
28 |
(9.8) |
0.524 |
136 |
(47.4) |
151 |
(52.6) |
0.303 |
| |
|
Controls |
133 |
(43.2) |
140 |
(45.5) |
35 |
(11.4) |
|
273 |
(88.6) |
35 |
(11.4) |
|
133 |
(43.2) |
175 |
(56.8) |
|
|
rs1800896 |
A>G |
Cases |
258 |
(89.6) |
29 |
(10.1) |
1 |
(0.3) |
0.701 |
287 |
(99.7) |
1 |
(0.3) |
0.601 |
258 |
(89.6) |
30 |
(10.4) |
0.452 |
| Controls | 269 | (87.6) | 36 | (11.7) | 2 | (0.7) | 305 | (99.3) | 2 | (0.7) | 269 | (87.6) | 38 | (12.4) | |||||
1: major allele; 2: minor allele.