Figure 1. A schematic representation of RB1CC1, immunogens, and epitope sites for four kinds of monoclonal antibodies (N1-8, N1-216, N3-2, and N3-42).

Two recombinant polypeptides of RB1CC1 containing amino acid (aa) residues 25–271 (N1) and 549–819 (N3), respectively, were used as immunogens. N1-216, N1-8, N3-2, and N3-42 antibodies recognize epitopes within aa residues 235–254, 255–271, 715–734, and 715–734, respectively, of RB1CC1.