Table 1. Summary of immunoreactive variations between N1-8 monoclonal and polyclonal antibodies in a series of 57 clinical breast cancer cases.
N1-8 monoclonal | ||||||
(−) | (+) | Cases | ||||
cytoplasm | ||||||
(−) | (+) | |||||
N1-polyclonal | ||||||
cytoplasm | ||||||
(−) | (−) | 4 | 5 | 0 | 9 | |
(+) | 2 | 8 | 0 | 10 | 19 | |
(+) | 0 | 0 | 38 | 38 | ||
6 | 13 | |||||
19 | 38 | 57 |
Although N1-8 could recognize cytoplasmic RB1CC1 better than the polyclonal antibody (13 vs 10 cases), both antibodies were completely consistent in recognizing the nuclear reactivity of RB1CC1.