Table 1. Cancer chemotherapeutics induce IFN-β secretion (ELISA assay).

	IFN-β (pg/ml)	Fold Increase
DMSO	25.0	1.0
TPT	99.8	4.0
etoposide	86.6	3.5
cisplatin	67.3	2.7
paclitaxel	68.4	2.7
vinblastine	71.1	2.8

ZR-75-1 cells were treated with topotecan (40 nM), etoposide (1 µM), cisplatin (6 µM), paclitaxel (3 µM), or vinblastine (6 nM) for 24 hrs, aspirated and washed, followed by incubation in drug-free medium for 3 days. Levels of IFN-β protein in the culture media were then measured by ELISA.