Figure 1.

Telomere length according to age in patients with DC and their relatives. The vertical axis represents telomere length in kb. The curved lines in the figures indicate the 1^st, 10^th, 50^th, 90^th, and 99^th percentiles of results from 400 normal controls. Colored symbols represent patients with DC and their relatives. Red circles: classical DC patients; green triangles: Hoyeraal-Hreidarsson; black diamonds: revesz syndrome; blue squares: silent carriers; open black squares: DC relatives in families with unknown genes; open black triangles: DC relatives without mutations in the probands’ genes. Top panels show granulocytes, lymphocytes, and CD45RA-positive/CD20-negative naïve T cells. Bottom panels show CD45RA-negative memory T cells, CD20-positive B cells, and total NK/NKT cells.