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LiCl treatment in chondrocytes results in high expression of MMP-13. MMP-13 protein (a, detected by immunofluorescent microscopy, ×200) and mRNA (c) were significantly higher in LiCl-treated chondrocytes in eight week old rats, as compared to non-treated chondrocytes. MMP-13 mRNA expression levels in normal cartilage were not significantly different at different ages (b)
