Table 2.
Biochemical Results in Pregnant Adolescents and in their Neonates at Birth1
| All Subjects | African American | Caucasian | Comparison Between Races2 | |
|---|---|---|---|---|
| 25(OH)D (ng/mL) | ||||
| Mid-Gestation % ≥ 20 (n) |
22.1 ± 10.2 a 52.4% (166) |
20.5 ± 9.9 a 60.6% (110) |
22.5 ± 9.8 a 35.7% (56) |
p < 0.001 |
| Delivery % ≤ 20 (n) |
21.5 ± 11.6a 50.3% (137) |
19.8 ± 10.1 a 54.0% (87) |
24.4 ± 13.4a 42.0% (50) |
p < 0.05 |
| Cord Blood % ≤ 20 (n) |
20.8 ± 10.2a 52.8% ≤ 20 (123) |
16.6 ± 9.4a 61.5% (50) |
24.6 ± 10.6a 37.8% (45) |
p < 0.0001 |
| iPTH (pg/mL) | ||||
| Mid-Gestation % > 46 (n) |
28.7 ± 16.0a 12.1% (91) |
32.2 ± 18.2a 19.6% (56) |
23.0 ± 9.4a 0% (35) |
p < 0.01 |
| Delivery % > 46 |
45.1 ± 29.4b 40.0% |
47.1 ± 33.2b 43.1% |
41.5 ± 21.0 b 34.5% |
- |
| (n) | (80) | (51) | (29) | |
| Cord Blood % > 46 (n, % detectable) |
19.0 ± 12.1c 0% (33, 37%) |
19.3 ± 12.2c 0% (22, 39%) |
18.2 ± 12.5c 0% (11, 33%) |
- |
| 1,25(OH)2D (pg/mL) | ||||
| Mid-Gestation (n) |
117 ± 30a (100) |
118 ± 30a (63) |
115 ± 31a (37) |
- |
| Delivery (n) |
106 ± 31b (96) |
111 ± 31b (63) |
97 ± 29b (33) |
p < 0.05 |
| Cord Blood (n) |
48 ± 19c (74) |
48 ± 17c (49) |
46 ± 23 c (n = 25) |
- |
| Serum Ca (mg/dL) | ||||
| Mid-Gestation (n) |
9.0 ± 0.4a (156) |
9.0 ± 0.4a (101) |
9.1 ± 0.4a (55) |
- |
| Delivery (n) |
9.0 ± 0.4a (133) |
9.0 ± 0.4a (85) |
9.0 ± 0.4a (48) |
- |
| Cord Blood (n) |
10.4 ± 0.7b (124) |
10.4 ± 0.7b (77) |
10.4 ± 0.7b (47) |
- |
| Serum OC (ng/mL) | ||||
| Mid-Gestation (n) |
3.7 ± 1.3a (152) |
3.5 ± 1.3a (90) |
3.9 ± 1.3a (50) |
- |
| Delivery (n) |
4.9 ± 2.5b (128) |
4.7 ± 2.5b (81) |
5.4 ± 2.4b (45) |
p < 0.05 |
| Cord Blood (n) |
15.1 ± 8.3c (114) |
14.9 ± 8.8c (74) |
15.4 ± 7.4c (40) |
- |
| Serum NTX (nmol/BCE) | ||||
| Mid-Gestation (n) |
10.7 ± 3.8a (152) |
10.6 ± 3.8a (97) |
10.9 ± 3.9a (55) |
- |
| Delivery (n) |
16.9 ± 7.8b (124) |
16.0 ± 6.4b (79) |
18.5 ± 9.7b (45) |
- |
| Cord Blood (n) |
64.4 ± 19.7c (112) |
66.9 ± 18.8c (71) |
60.2 ± 20.8c (41) |
- |
1
Data are reported as the Mean ± SD, or percentage, with the sample size in parentheses. Mid-Gestation = 26.3 ± 3.6 weeks; Delivery = 39.2 ± 2.9 weeks.
2
P value given for comparison between races at each time-point (horizontal comparison) Different letter superscripts indicate statistically different concentrations between Mid-Gestation, Delivery, and Cord Blood values (vertical comparison), controlling for participant ID as a fixed effect and correcting for multiple comparisons; p < 0.05.