Table 1.

Model parameters

Parameter	Value	Units
Sarcomere geometry
LA (length of AF)	1.2	μm	*
LM (length of MF)	1.65	μm	*
LB (length of B-zone)	0.1	μm	*
nu (number of MHs)	36	Unitless	*
Transition rates Ca-bound
K on	80	μM−1 s−1	**
K off	80	s−1	**
\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ K^{\prime}_{\text{on}} $$\end{document}	80	μM−1 s−1	**
\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$ K^{\prime}_{\text{off}} $$\end{document}	8	s−1	**
Transition rates N–P			**
Q 0	3	Unitless	**
SL Q	2.2	μm	**
α Q	1.4	μm−1	**
K basic	10	s−1	**
μ	10	Unitless	**
γ	40	Unitless	**
SL dependence
a R	0.1	μm
a L	0.1	μm
Time interval lengths
DT (for averaging in MC)	2.5	ms
Δt	2.5	μs

Parameter values were adopted * from Rice et al.,20 ** from Rice et al.19 with modifications