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. Author manuscript; available in PMC: 2013 Feb 28.
Published in final edited form as: Biochemistry. 2012 Feb 16;51(8):1617–1624. doi: 10.1021/bi3000935

Figure 7. Interdomain interactions of Ser140 in rod Gαt1 are lost in the S140A mutant.

Figure 7

In the structure of Gαt1GDP (24), Gαt1Ser140 from the helical domain interacts with Asp227 and Lys273 from the Ras-like domain (left). The S140A mutation was introduced into the structure of Gαt1GDP using the Swiss-PdbViewer (v.4) (44). The mutation disrupts the interdomain interactions in Gαt1GDP (right). The images were produced using PyMOL 1.4.1 (45).