Table 1.

Overview of selected α7 nAChR antagonists.

Name	Structure	Source	Use	Reference
α-bungarotoxin	8 kDa globular protein	Taiwanese krait Bungarus multicinctus	not used in therapy, natural toxin	[77–79]
CnIA, PnIA	polypeptide	α-conotoxins from cone snail Conus consors	natural toxin, use in research for distinguishing of acetylcholine receptors types	[70–75]
HI-6 (also known as asoxime)	1-[(4-carbamoylpyridin-1-ium- 1-yl)methoxymethyl]pyridin-1- ium-4- carboxamide dichloride CAS: 34433-31-3	byspyridinium oxime derivative	therapy of nerve agents poisoning via reactivation of AChE	[85–89]
memantine	3,5-Dimethyltricyclo[ 3.3.1.13,7]decan-1- amine hydrochloride CAS: 19982-08-2	adamantane derivative	Alzheimer’s disease drug antagonizing NMDA receptor, antagonism of α7 nAChR is a side pathway	[80–82]
methylcaconitine	683 Da alkaloid CAS: 21019-30-7	Consolida flowers	not used in therapy, natural toxin	[83–84]