α-bungarotoxin |
8 kDa globular protein |
Taiwanese krait Bungarus multicinctus
|
not used in therapy, natural toxin |
[77–79] |
CnIA, PnIA |
polypeptide |
α-conotoxins from cone snail Conus consors
|
natural toxin, use in research for distinguishing of acetylcholine receptors types |
[70–75] |
HI-6 (also known as asoxime) |
1-[(4-carbamoylpyridin-1-ium- 1-yl)methoxymethyl]pyridin-1- ium-4- carboxamide dichloride CAS: 34433-31-3 |
byspyridinium oxime derivative |
therapy of nerve agents poisoning via reactivation of AChE |
[85–89] |
memantine |
3,5-Dimethyltricyclo[ 3.3.1.13,7]decan-1- amine hydrochloride CAS: 19982-08-2 |
adamantane derivative |
Alzheimer’s disease drug antagonizing NMDA receptor, antagonism of α7 nAChR is a side pathway |
[80–82] |
methylcaconitine |
683 Da alkaloid CAS: 21019-30-7 |
Consolida flowers |
not used in therapy, natural toxin |
[83–84] |