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Methemoglobinemia induced by 3-aminopyridine-2-carboxaldehyde thiosemicarbazone.
| Number of patients | 3-AP dose (mg/m2) | Infusion length (h) | Reaction | Mean pulse O2 saturation (%) | Mean peak methemoglobin (%) | Ref. |
|---|---|---|---|---|---|---|
| 1 | 105 | 2 | Dyspnea, hypertension | 75 | 12 | [20] |
|
| ||||||
| 2 | 105 | 4 | Dyspnea, pallor | 88 | 11 | |
|
| ||||||
| 6 | 25 | 2 | None | 96 | 1 | [15] |
|
| ||||||
| 4 | 50 | 2 | None | 94 | 6 | |
3-AP: 3-aminopyridine-2-carboxaldehyde thiosemicarbazone.
