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Adipose tissue and circulating CX3CL1 levels are increased in human endotoxemia. Adipose tissue relative mRNA expression (A) and protein levels (B) were increased by both 3 ng/kg and 0.6 ng/kg endotoxin. C: Plasma levels were also increased by both endotoxin doses. Closed circles and solid line denote 3 ng/kg endotoxin; open circles and dashed line denote 0.6 ng/kg endotoxin. Values shown are mean ± SD. *P < 0.001; **P < 0.0001 compared with pre-endotoxin (time 0) levels.
