FIG. 4.

CX3CL1 modulates adhesion of human monocytes to primary human adipocytes. A: Mean number (± SD) of fluorescent THP-1 monocytes adherent to primary adipocytes were counted per HPF in each experimental condition. The groups designated for each block refer to blocking antibodies used in the condition. *P < 0.0001 compared with negative antibody; **P < 0.005 compared with CX3CL1 alone. Representative images for negative antibody (B), CX3CL1 antibody (C), MCP-1 antibody (D), and both CX3CL1 and MCP-1 antibodies (E) are shown. (A high-quality digital representation of this figure is available in the online issue.)