Table 1.

Odds ratio of COX-2 positive expression by selected breast cancer prognostic factors

Prognostic factor		COX-2 positive		COX-2 negative	OR (95% CI)
	N	%	N	%
Overall	561	28.0	1440	72.0
Stage
1	252	25.2	748	74.8	1.00
2	186	28.1	476	71.9	1.16(0.93–1.45)
3	107	36.2	189	63.9	1.68(1.27–2.22)
4	16	37.2	27	62.8	1.76(0.93–3.32)
Grade
1	48	35.3	88	64.7	1.00
2	115	27.1	309	72.9	0.68(0.45–1.03)
3	104	26.7	285	73.3	0.67(0.44–1.02)
missing	294	28.0	758	72.1	---
Tumor size (cm)
≤1	127	25.5	372	74.6	1.00
1.1–2.0	203	26.5	564	73.5	1.05(0.82–1.36)
2.1–4.0	162	29.9	380	70.1	1.25(0.95–1.64)
>4.0	67	35.5	122	64.6	1.61(1.12–2.31)
missing	2	50.0	2	50.0	---
Lymph nodes
0	337	25.3	994	74.7	1.00
1–3	120	31.9	256	68.1	1.38(1.08–1.78)
4–9	52	34.0	101	66.0	1.52(1.06–2.17)
≥10	36	36.7	62	63.3	1.71(1.12–2.63)
Metastatic at diagnosis	16	37.2	27	62.8	1.75(0.93–3.28)
Histology
Ductal	462	27.2	1236	72.8	1.00
Lobular	67	34.4	128	65.6	1.40(1.02–1.92)
missing, other	32	29.6	76	70.4	---
ER status
Negative	68	17.4	323	82.6	1.00
Positive	414	31.8	888	68.2	2.22(1.66–2.95)
missing	79	25.7	229	74.4	---
PR status
Negative	130	22.4	450	77.6	1.00
Positive	320	32.1	676	67.9	1.64(1.29–2.08)
missing	111	26.1	314	73.9	---
HER2 status
Negative	498	28.6	1229	71.4	1.00
Positive	58	26.2	163	73.8	0.89(0.65–1.22)