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Histology of rd10 mice retinas treated with TUDCA or control at P38. Outer nuclear layer thickness averaged 9.2 μm in controls versus 11.3 μm in the treated animals. The difference in ONL thickness was significant at P = 0.0006 (paired t-test). H&E-stained photomicrographs depict (a) C57Bl6, (b) TUDCA-treated rd10, and (c) vehicle-treated rd10 mice. Scale bar, 100 μm.
