Table 1.

Measures of Axon and Myelin Integrity Measured by DTI and Histology

Measure	Axon				Myelin
	Axial Diffusivity (μm2/ms)	SMI-31	SMI-32	SMI-312	Radial Diffusivity (μm2/ms)	MBP
Control	0.59 ± 0.06	5900 ± 800	0 ± 0	5900 ± 400	0.08 ± 0.1	5300 ± 900
3DPI	0.45 ± 0.07*	3000 ± 500†	500 ± 200†	3400 ± 400†	0.09 ± 0.1	5400 ± 400
7DPI	0.45 ± 0.06*	1600 ± 600†	1100 ± 300†	2900 ± 800†	0.12 ± 0.1†	3200 ± 600†

Data are presented as mean ± SD (n = 8 for DTI measurement, n = 5 for immunohistochemistry analysis).

^*P < 0.05;

^†P < 0.005, compared with controls.