Table 1.
Baseline Characteristics of Patients in SCUT: Comparison between P. aeruginosa and All Other Bacterial Ulcers
| P. aeruginosa (n = 110) | All Other Bacteria* (n = 384) | P | |
|---|---|---|---|
| Age in years, median (IQR) | 43 (30–54) | 55 (42.5–63) | <0.001† |
| Sex, n (%) | 0.051‡ | ||
| Male | 69 (63) | 199 (52) | |
| Female | 41 (37) | 185 (48) | |
| Duration of symptoms, n (%) | 0.008‡ | ||
| <4 days | 55 (50) | 144 (38) | |
| 4–7 days | 42 (38) | 151 (39) | |
| 8–14 days | 10 (9) | 44 (11) | |
| >14 days | 3 (3) | 45 (12) | |
| Contact lens use, n (%) | 7 (6) | 1 (0.2) | <0.001‡ |
| Systemic disease,§n (%) | 6 (5) | 21 (5) | >0.99‡ |
| Ulcer location, n (%) | 0.007‡ | ||
| Entirely in periphery | 9 (8) | 56 (15) | |
| Partially covering 4 mm | 65 (59) | 253 (66) | |
| Completely fills 4 mm | 36 (33) | 73 (19) | |
| Visual acuity, logMAR, median (IQR) | 1.26 (0.46–1.7) | 0.74 (0.35–1.6) | 0.002† |
| Infiltrate/scar size in mm, median (IQR) | 3.8 (2.5–5.6) | 2.5 (1.8–3.7) | <0.001† |
| Treatment arm, n (%) | 0.45‡ | ||
| Corticosteroid | 59 (54) | 188 (49) | |
| Placebo | 51 (46) | 196 (51) |
Other bacteria include Streptococcus pneumoniae (n = 250), Nocardia spp. (n = 56), coagulase-negative Staphylococcus (n = 22), Staphylococcus aureus (n = 16), Moraxella spp. (n = 15), Viridans group Streptococcus (n = 11), Corynebacterium spp. (n = 6), Bacillus spp. (n = 1), Mycobacteria spp. (n = 1), Klebsiella spp. (n = 3), Enterobacter spp. (n = 2), Haemophilus influenzae (n = 1), other Pseudomonas spp. (non-Aeruginosa, n = 3), other Gram-positive (n = 3), and Gram-negative bacteria (n =5).
Rank sum test.
Fisher's exact test.
Systemic diseases included diabetes, asthma, Hansen's disease, eczema, psoriasis, HIV, ichthyosis, and malnutrition.