A model of differential distribution of xlProminin-1 and peripherin-2/rds in rod and cone photoreceptors. xlProminin-1 (green) distributes to the outer rims of open disk lamellae of COS and basal disks of ROS. Peripherin-2/rds, in contrast, distributes to the inner rim on the same side as the connecting cilium in COS and also to the entire rim of closed mature disks in ROS. Prominin-1 is also sparsely present throughout the entire disks of ROS. CC, connecting cilium; OD, oil droplet; N, nucleus.