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. 2012 Feb 23;7:1091–1100. doi: 10.2147/IJN.S28694

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© 2012 Wei et al, publisher and licensee Dove Medical Press Ltd.

This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

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(A) Loading efficiency of CNN2 (connective tissue growth factor) in nanotubes; fraction of total CNN2 released from 100 nm diameter nanotubes filled with (B) 25 ng and (C) 50 ng of CNN2; (D) fraction of total CNN2 released from 120 nm diameter nanotubes filled with 50 ng of CNN2.

Notes: The marked time point on each graph indicates when maximum protein has been released, after which the amount of additional drug eluted was negligible. Concentrations at these time points are significantly different from those at time points before (P < 0.05), but were not significantly different from the time points after; n = 3.