Table 6.
Correlations between ECM1 expression and clinicopathological characteristics
| Clinicopathological characteristics | N | ECM1 positive | P | ECM1 mRNA expression | P | |
|---|---|---|---|---|---|---|
| N | rate (%) | |||||
| Age (years) | ||||||
| < 60 | 30 | 22 | 73.3 | 1.54 ± 0.43 | ||
| ≥ 60 | 11 | 9 | 81.8 | 0.700 | 0.68 ± 0.46 | 0.183 |
| Histological grade (invasive ductal) |
||||||
| I+II | 16 | 12 | 75.0 | 1.76 ± 0.71 | ||
| III+IV | 20 | 16 | 80.0 | 0.720 | 1.18 ± 0.39 | 0.483 |
| Tumor size | ||||||
| T1 | 15 | 10 | 66.7 | 1.49 ± 0.60 | ||
| T2 | 23 | 19 | 82.6 | 1.34 ± 0.46 | ||
| T3 | 3 | 2 | 66.7 | 0.512 | 0.11 ± 0.08 | 0.275 |
| Lymph nodal status | ||||||
| N0 | 22 | 16 | 72.7 | 1.48 ± 0.54 | ||
| N1 | 12 | 10 | 83.3 | 1.32 ± 0.58 | ||
| N2 | 5 | 3 | 60.0 | 0.81 ± 0.60 | ||
| N3 | 2 | 2 | 100 | 0.121 | 0.54 ± 0.50 | 0.424 |
| Estrogen receptor status | ||||||
| - | 10 | 5 | 50.0 | 1.02 ± 0.62 | ||
| +~+++ | 31 | 26 | 83.9 | 0.045* | 1.40 ± 0.41 | 0.611 |
| Progesterone receptor status | ||||||
| - | 8 | 4 | 50.0 | 1.32 ± 0.90 | ||
| +~+++ | 33 | 27 | 81.8 | 0.082 | 1.30 ± 0.37 | 0.987 |
| HER2/neu score | ||||||
| - (0-1) | 13 | 11 | 84.6 | 1.48 ± 0.69 | ||
| + (2-3) | 28 | 20 | 71.4 | 0.458 | 1.23 ± 0.39 | 0.757 |
"+", "++" and "+++" for ECM1 immunochemistry staining was all grouped together as "+"
* P < 0.05 is considered statistically significant