Table 6. Dependancy of correlations on medication.

Correlations between plasma homocysteine and betaine excretion in:	Above median betaine excretion			Below median betaine excretion
	n	r	p	n	r	p
Subset based on drug treatment:
All subjects without diabetes	73	+0.25	0.032	87	−0.24	0.025
No diuretics	52	+0.21	0.13	61	+0.12	0.36
With diuretics	17	+0.11	0.67	26	−0.42	0.033
No beta blocker	7	+0.57	0.18	14	+0.12	0.67
With beta blocker	65	+0.26	0.035	73	−0.30	0.010
No ACE inhibitor	38	+0.13	0.42	36	−0.36	0.036
With ACE inhibitor	34	+0.43	0.011	51	−0.15	0.30
No clopidogrel	43	+0.11	0.49	58	−0.15	0.26
With clopidogrel	29	+0.46	0.012	29	−0.37	0.050
No calcium channel blocker	46	+0.10	0.52	61	−0.19	0.14
With calcium channel blocker	26	+0.39	0.051	26	−0.21	0.31
No proton pump inhibitor	45	+0.32	0.032	52	+0.01	0.95
With proton pump inhibitor	28	+0.17	0.38	35	−0.42	0.011

All data on subjects with above median plasma non-HDL-cholesterol and with subjects with diabetes excluded. Pearson's correlation coefficients between log (plasma tHcy) and log(urine betaine/creatinine). Bold significant (p<0.05).