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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Hippocampus. 2011 Aug 18;22(6):1363–1370. doi: 10.1002/hipo.20972

FIGURE 5.

FIGURE 5

Effect of circadian cycle on LTP but not concurrent LTD. (A) Pre-HFS waveforms (dashed lines) are averages of 30 sweeps sampled immediately before 400 Hz-DBS; post-HFS waveforms (solid lines) are averages of the final 30 sweeps obtained at 45 to 60 min. Scale bar: 5 mV, 5 μs. (B) No significant differences in the induction of LTP and concurrent LTD compared across the dark and light phases. (C) Comparison across the subsequent 35 days revealed slight but significantly greater LTP at days 7 and 14 during the dark phase. No significant circadian differences were observed in the persistence of lateral path LTD.