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. 2011 Nov 22;61(4):543–553. doi: 10.1136/gutjnl-2011-301012

Figure 1.

Figure 1

Metabolic adaptation after 3 months of high-fat diet (HFD) and change in phenotype by supplementation of HFD with gluco-oligosaccharides (GOS). (A) Timeline of the experimental protocol. (B) Intraperitoneal glucose tolerance test (IPGTT) in HFD-fed mice that became diabetic (HFD-D, closed squares, n=24), diabetes-resistant (HFD-DR, open squares, n=10) or fed a GOS-supplemented HFD (HFD+GOS, closed triangles, n=10). Data are shown as mean ± SEM; *p<0.05, ***p<0.001 (HFD-D vs HFD-DR) and §§§p<0.001 (HFD-D vs HFD+GOS) (two-ANOVA and Bonferroni post test). (C) Glycaemic index; ***p<0.001 (unpaired Student t test).